vH2O2 bio-decontamination measurement, monitoring and control

Effective processes, cycle development, and validation

Vaporized hydrogen peroxide is a safe and environmentally friendly way of performing bio-decontamination in isolators, hospital rooms, transfer hatches and other applications. Vaporized H2O2 concentration levels and other parameters are measured during bio-decontamination to provide in-process control and ensure process conditions have been achieved.

To maintain sensor accuracy over multiple bio-decontamination processes, the PEROXCAP sensor has two internal features: sensor warming and purge function. The warming prevents condensation on the sensor and the purge function cleans the sensor membrane from potential contaminants. The intelligent measurement technology of the HPP270-series probes helps maintain measurement accuracy between calibration intervals – even in challenging, high-humidity bio-decontaminations.   

  • Isolators, cRABS
  • Transfer Hatches & chambers
  • Vapor generators
  • Incubators and chambers
  • Production lines
     

H2O2 Measurement: Relative Saturation

PEROXCAP® sensor technology uses two HUMICAP® sensors; one is a standard HUMICAP sensor and the other includes a catalytic layer that prevents H2O2 molecules from entering the sensor membrane and senses only the water vapor part of the air mixture. The HPP272 probe has an additional RTD temperature probe to monitor process temperature with humidity (both relative humidity and relative saturation). Dew point and vapor pressure measurements are possible, often critical parameters in bio-decontamination. The HPP271 probe option measures H2O2 ppm by volume.

DOWNLOAD THE BIO-DECONTAMINATION GUIDE

Benefits of PEROXCAP®

  • Unique capacitive thin-film polymer sensors for repeatable measurement
  • Stable even in high humidity bio-decontamination conditions
  • Multiple measurements from a single device
  • Onsite calibration or traceable factory calibration
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The Vaisala PEROXCAP® HPP270 series probes

The Vaisala PEROXCAP® HPP270 series probes feature both digital and analog outputs.  In addition to H2O2, the probe measures temperature and humidity, referring to relative saturation and relative humidity, dew point, and vapor pressure. The probes can be used for both monitoring and control. Another unique feature of the HPP270 series probes is the ability to evaluate the sensors’ performance through its “Sensor Vitality” value. This value provides on-going diagnostics on sensor function.  

The probes can be used with the optional Vaisala Indigo transmitters or as standalone probes. Indigo transmitters provide an easy user interface and can be configured according to process requirements. Indigo comes with plug-and-play probe connection, LCD color display (optional non -display version for analog model), and IP65 enclosure. For simple probe configuration, calibration, and adjustment, the probe can be connected to Vaisala's Insight PC software.
 

HPP270 Series

vH2O2 Calculator

With this vaporized hydrogen peroxide calculator, you can simulate bio-decontamination processes in closed and open systems, or under free evaporation conditions. Simply choose your method and input parameters like: phase duration, temperature, injection rates, H2O2 liquid concentration, and other parameters. Model your process in the simulator and see the effects on the condensation point, relative humidity, relative saturation, and achievable vH2O2 ppm concentration.

How to use: 

  • Choose your bio-decontamination method: Closed system, Open system, free evaporation
  • Enter process parameters
  • View results

See also our webinar on using the vH2O2 calculator

TRY THE CALCULATOR

Vaporized Hydrogen Peroxide Measurement related products

Indigo520 with probe

Indigo500 Series Transmitters

The Vaisala Indigo500 series transmitters are host devices for Vaisala Indigo-compatible, stand-alone smart probes. The Indigo500 series include multi-functional Indigo520 transmitter and Indigo510 transmitter with basic features.

Further Reading on Vaporized Hydrogen Peroxide Bio-decontamination

Calculator

vH2O2 Calculator

With this vaporized hydrogen peroxide calculator, you can simulate bio-decontamination processes in closed and open systems, or under free evaporation conditions. Simply choose your method and input parameters like: phase duration, temperature, injection rates, H2O2 liquid concentration, and other parameters. 

Learn more

Webinar

vH2O2 Calculator: How to simulate conditions in bio-decontamination processes

Learn how to simulate bio-decontamination conditions in closed and open systems, or under free evaporation conditions using our online H2O2 Calculator.

Register to watch

eBook

Hydrogen peroxide vapor technical eBook

In this technical eBook you will learn the fundamental conversion formulas that pertain to hydrogen peroxide vapor. These formulas allow you to make your own calculations.

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Blog

Vaporized Hydrogen Peroxide (H2O2) Vs. Vaporized Ethylene Oxide (EtO)

Vaporized hydrogen peroxide is an easy-to-use, safe, low-temperature bio-decontamination agent in equipment and facilities used within the life science industry and healthcare facilities.

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Blog

Vaporized Hydrogen Peroxide Bio-Decontamination Q&A

In our webinars we have gone through several topics related to H2O2 bio-decontamination and we have received a lot of questions.

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Blog

Field Comparison of Hydrogen Peroxide Measurement Systems for Isolators

Vaisala supplied Nieskes with a Vaisala HPP272 probe combined with the Indigo201 transmitter for testing purposes.

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Application note

Vaporized Hydrogen Peroxide Bio-Decontamination in Isolators, cRABS, and Transfer Hatches

In this application note, we look at vaporized hydrogen peroxide in isolators, closed restricted access barrier systems (cRABS), and transfer hatches (TH). Although the focus is on isolator bio-decontamination, the same principles also apply to other safety and purity units.

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Application note

Field Comparison of Hydrogen Peroxide

Hydrogen peroxide generators are used for room bio-decontamination in intensive care units, operating and emergency rooms, ambulances, blood banks, food and beverage processing and storage areas, animal facilities and labs, procedure rooms and more... In this application note we outline the use of vaporized hydrogen peroxide in large chambers and rooms.

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Blog

Comparing Four Different Hydrogen Peroxide Bio-Decontamination Validation Processes

There are different ways to verify that a vaporized hydrogen peroxide bio-decontamination process is working effectively, each with its own pros and cons.

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