Production of Active Pharmaceutical Ingredients (API)

Developing and producing Active Pharmaceutical Ingredients (APIs) includes various processing steps, such as reaction, crystallization, separation and purification, filter cake washing, solvent swap, and solvent exchange.

Production of Active Pharmaceutical Ingredients (API)

Download our application note and learn how, by utilizing real-time concentration measurements by Vaisala K-PATENTS® Pharma Refractometer, the pharmaceutical manufacturers can:

  • Follow the reaction and determine the correct endpoint.
  • Automatically control the feeding valves.
  • Monitor solvent swap operation.
  • Monitor mother liquor concentration and determine seeding point.
  • Help to understand the washing process, create washing profiles, and find the most suitable washing solvent.
  • Help to understand the process and create a process profile for reference in scale-up.
  • Be used for critical process parameter (CCP) identification.

The application note explains in more detail the benefits of using the pharma refractometer. The note also includes recommended installation points for best performance, and shortly introduces the reliable technology our pharma refractometer is based on.

Download the application note (PDF) by filling the form.

Watch our webinar on The benefits of refractive index (RI) in the development and production of Active Pharmaceutical Ingredients (APIs)

Discover all applications in Pharmaceutical drug manufacturing and biotechnology processes.

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