Pharmaceutical fermentation

Fermentation is a process used for cultivating micro-organisms or other organic material into important pharmaceuticals such as antibiotics, therapeutic proteins, enzymes and insulin. It is typically carried out in temperature-controlled tanks (fermenter) which require addition of nutrients at the correct concentration to maximize productivity of the organism of interest.

Download our application note and learn how, by utilizing real-time concentration measurements by Vaisala K-PATENTS® Pharma Refractometer, the pharmaceutical manufacturers can:

  • Monitor continuously the degree of fermentation and fermentation conversion.
  • Gather understanding for identifying the fermentation endpoint.
  • Identify immediately the need for nutrients addition.
  • Control nutrients solution concentration and reduce costs by using only the amount required.
  • Automatically control fermenter feed-valves.

The application note is about fermentation operation, and it explains in more detail the benefits of using refractive index in pharmaceutical manufacturing and why refractometer is ideal for fermentation operation. The note also includes recommended installation points for best performance.

Download the application note (PDF) by filling the form.

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Pharmaceutical fermentation

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