Pharmaceutical crystallization

Crystallization is a key unit operation and an important step in processing and development within the pharmaceutical industry, and it is used in the separation and purification of intermediate compounds and Active Pharmaceutical Ingredients (APIs). Over 80% of drug products involving at least one crystallization step.

Download our application note and learn how, by utilizing real-time concentration measurements by Vaisala K-PATENTS® Pharma Refractometer, the pharmaceutical manufacturers can:

  • Monitor the concentration of mother liquor for optimum seeding point.
  • Control supersaturation.
  • Control nucleation and crystal growth rate.
  • Create solubility curves of APIs.
  • Create crystallization profiles at laboratory for scale-up processes.

The application note explains in more detail the benefits of using refractive index in pharmaceutical manufacturing and why refractometer is ideal for liquid-solid operations. The note also includes recommended installation points for best performance.

Download the application note (PDF) by filling the form.

Discover all applications in Pharmaceutical drug manufacturing and biotechnology processes.

Pharmaceutical crystallization

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