In this week's blog, Paul Daniel answers a few questions that we often receive on using mean kinetic temperature.
I have a couple questions regarding the mean kinetic temperature value for a recent temperature study of three of our warehouses here at our nutraceutical distribution center. We generated a "historical data report" using the Vaisala mapping software, however, we still have some uncertainties on what numbers we need and how to correctly read the report.
First, in the software we noticed under "Options > Historical Data Report Statistics" that we can change the values of the statistics time interval to our sample time of 14 days and this changes the sample time in the actual report. We also notice that we can change the MKT activation energy, which changes the MKT value in the report. But, here our interpretation is fuzzy. What exactly is the activation energy value and what should it be set at? Second, in the report, there are two columns labeled as Groups. What are these columns indicating?
Third, there is an MKT value on line 54 and a Min MKT value at line 68. Is there a Max MKT value?
Fourth, which MKT value is the correct one to use in our trending reports?
Finally, as stated, we are performing temperature studies every quarter of 2016 on three different warehouses. If we want to trend the MKT data over the course of year, is it best to take the average of all MKT scores to find a global average or is there a better calculation for trending the MKT score?
We appreciate your time and attention to our queries!
Thank you for contacting us! I always enjoy answering questions that are specific to our solutions ☺
Also, you are not alone in your questions – we are often asked about MKT. This is why we created a webinar on the topic. If you haven't already, please check it out:
a) Its inclusion was based on us simply following the reporting characteristics of another calculated value – Lethality (FO) – in which the minimum is important.
b) MKT is generally not a reported value for a group but is reserved for investigation of excursions, as you can't have a problem with MKT unless you already have a problem with your temperature values.
I hope this was helpful! Please contact us again if you need further assistance…
Paul Daniel is the Senior Regulatory Compliance Expert at Vaisala. He has worked in the GMP-regulated industries for over 20 years helping manufacturers apply good manufacturing practices in a wide range of qualification projects. His specialties include mapping, monitoring, and computerized systems.
At Vaisala, Paul oversees and guides the validation program for the Vaisala viewLinc environmental monitoring system. He serves as a customer advocate to ensure the viewLinc environmental monitoring system matches the demanding requirements of life science and regulated applications.
Paul also shares his GMP experience through regular blog contributions, webinars, and seminars around the world. Paul’s expertise in the demanding GxP world is applicable to any industry where measurement is critical to product quality. Paul is a graduate of University of California, Berkeley, with a bachelor's degree in biology.