Combating COVID-19 with H2O2 vapor bio-decontamination
According to the World Health Organization's interim guidance on laboratory biosafety, disinfection procedures for COVID-19 should include "Appropriate disinfectants with proven activity against enveloped viruses ... (e.g. hypochlorite (bleach), alcohol, hydrogen peroxide, quaternary ammonium compounds and phenolic compounds)."
Cleamix Oy, Finnish manufacturer of portable hydrogen peroxide vapor generators and a bio-decontamination service provider, uses Vaisala's HPP270 series hydrogen peroxide vapor sensors to control vapor output and monitor process conditions in areas under bio-decontamination.
We recently spoke with Cleamix CEO Panu Wilska about the company’s work with Korea’s Center for Disease Control (KCDC) in the wake of the corona virus outbreak.
“The KCDC has BSL-2 and BSL-3 laboratories with a total volume 2500 m3,” says Wilska. “Our bio-decontamination contract with our local partner BioAll included both. The labs were about in equal size, with multiple separate rooms, airlocks and corridors. To decontaminate we used four portable networked Cleamix vapor generators. Because we had no prior performance data on these areas, the initial dimensions were roughly 125m3 per generator, which was gradually increased to 200m3 and over per unit in successive segments.
“During the bio-decontamination process, the HPP270 probes showed that the H2O2 concentration was rising quite rapidly. The average treatment time per segmented area was seventy-five minutes, plus aeration time. Aeration was very fast as we could have the AC system turned on after each treatment.
Our bio-decontamination work took two working days; however, now that we know the layout and decontamination performance of these areas, the same work could be completed in one day. According to KCDC, the earlier procedure with different vendor took four days to complete.
“The process was validated by biological indicators to have achieved a 6 log kill. After seven days of incubation, the results were confirmed without any doubt – the process was 100% successful.”
This work was critical for South Korea, which mobilized quickly to deal with COVID-19. Describing his government’s approach to the Corona virus outbreak, South Korea’s vice health minister Kim Ganglip said, “First … public participation must be secured through openness and transparency. Second … respect creative thinking and use cutting-edge technology to develop the most effective means of response.”
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Learn more about Cleamix:
English http://cleamix.com/
COVID-19 (Corona virus) Informational Web sites
US CDC
- Information for Laboratories
- Interim Laboratory Biosafety Guidelines for Handling and Processing Specimens Associated with Coronavirus Disease 2019 (COVID-19)
- Environmental Cleaning and Disinfection Recommendations (Households)
I am Chris Basilides from the Philippines
thanks so much