Stop timing, start measuring: inline RI in media and buffer preparation

Inline refractive index in biopharma
Liquid Measurements
Two sessions to choose from

Join Vaisala's expert to discuss how inline refractive index (RI) measurement shows you when your media or buffer is actually ready and on spec, not just when the timer says it should be.

A recipe and a stopwatch can't confirm that the last powder has dissolved, or that every addition went in as planned. If a batch comes out off spec, you're left with a tough call: discard it, or risk a cell culture run with lower yield, more variability and tougher downstream purification.

With inline RI, you see the whole dissolved composition, including sugars and other nonionic components that pH and conductivity miss. You can follow each addition, dissolution step and dilution as it happens. That matters most in continuous manufacturing, where off-spec media or buffer can compromise the whole process, not just one batch.

In this webinar, you'll learn how to:

  • Confirm each component addition is on target
  • Spot the true dissolution endpoint and optimize mixing time
  • Catch dilution errors in real time, between offline osmolality checks 
  • Carry one RI target from the development lab to production and across sites
  • Build a digital batch record that moves you closer to real-time release

Pick the session that suits your time zone and bring your questions. Our expert will answer them live.

Register now

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Tamara Murusidze Vaisala

Webinar Speaker: Tamara Murusidze

For more than 15 years, Tamara Murusidze has helped process engineers measure what happens inside their liquids, as it happens. She specializes in inline liquid analysis for biopharmaceutical and chemical pharmaceutical production, where real-time concentration data gives teams tighter process control and fewer surprises at the end of a batch.

At Vaisala, Tamara works with biopharma and life science manufacturers to apply inline refractive index measurement across development, scale-up and production. Before joining Vaisala, she was Product Manager in the Liquid Analysis Division at Tecnova HT. There she specialized in inline concentration measurement using refractive index, ultrasound velocity and optical methods, along with viscosity, turbidity and wastewater monitoring.

Her background spans both technical and commercial roles across Europe, so she understands the measurement physics as well as the realities of the production floor. Tamara holds a Professional Master’s Degree in the Commercialization of Scientific Instruments from Aix-Marseille University and a degree in Electronics from the National Technical University of Ukraine (Kyiv Polytechnic Institute).

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