Vaisala Polaris™ pharma refractometer is designed for pharmaceutical and biotechnology manufacturing, to measure liquid concentrations inline (in-situ); from laboratory-scale to pilot batches that are used in process development to the production-scale batches needed to support commercialization. This technical solution can improve the understanding of critical process parameters (CCP), reduce drug development time, increase production capacity and stability, improve product quality and safety, as well as demonstrate compliance with regulations. Example applications include processing of active pharmaceutical ingredients (APIs), biochemical/biopolymers, including vaccines, antibiotics, proteins and buffer solutions. Perfect PAT tool.